diff --git a/library/modules/Job.cpp b/library/modules/Job.cpp
index 1976d2e12..869a6b329 100644
--- a/library/modules/Job.cpp
+++ b/library/modules/Job.cpp
@@ -387,7 +387,14 @@ bool DFHack::Job::removeJob(df::job* job) {
     // call the job cancel vmethod graciously provided by The Toady One.
     // job_handler::cancel_job calls job::~job, and then deletes job (this has
     // been confirmed by disassembly).
-    world->jobs.cancel_job(job);
+
+    // HACK: GCC (starting around GCC 10 targeting C++20 as of v50.09) optimizes
+    // out the vmethod call here regardless of optimization level, so we need to
+    // invoke the vmethod manually through a pointer, as the Lua wrapper does.
+    // `volatile` does not seem to be necessary but is included for good
+    // measure.
+    volatile auto cancel_job_method = &df::job_handler::cancel_job;
+    (world->jobs.*cancel_job_method)(job);
 
     return true;
 }